"Dr.Nina is the best thing that happened to my skin! She is so professional and knowledgeable. I have struggled with acne all my life and just after two months of personalised skincare routine it is completely gone. I also got Profhilo, botox and a little filler to even out my face shape - I’m so happy with the natural results! She’s incredible!!"
Treatments · Facial Sculpting
JULÄINE™ Bio-Stimulator Treatment
A PLLA-based collagen bio-stimulator that works with your skin’s own regenerative processes — delivered as a course by Dr Nina Bal at Facial Sculpting in South Kensington to gradually restore firmness, smoothness and radiance from within, for natural-looking results that build over the months following treatment.
- Treatment
- Minimally invasive PLLA bio-stimulator
- Best for
- Collagen stimulation, firmness & skin quality
- Downtime
- Minimal — small bruises or swelling may occur
- Sessions
- A course of 2–3, about a month apart
- Results build
- Gradually over weeks · last 12–24 months
- From
- £1,400 per course — consultation first
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Save Face Platinum accredited
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Treatment summary
JULÄINE™ Bio-Stimulator Treatment at a glance
JULÄINE™ is a poly-L-lactic acid (PLLA) bio-stimulator delivered by injection to encourage your own fibroblasts to produce fresh collagen and elastin. It is designed to gradually restore firmness, smoothness and radiance over a planned course, with results that develop over weeks and, according to the manufacturer, can last 12–24 months. Unlike a filler, it does not add instant volume; results are gradual and vary from person to person.
- What it treats
- Loss of firmness & elasticity, fine lines, tired or lacklustre skin
- How it works
- PLLA stimulates your own fibroblasts to build fresh collagen & elastin
- Areas
- Face and other areas of collagen loss, assessed individually
- Anaesthetic
- Usually none; numbing cream may be used for comfort
- Sessions
- A course of 2–3 sessions, about a month apart
- Downtime
- Minimal; redness, swelling or small bruises may occur
- Results & longevity
- Build gradually over weeks; can last 12–24 months per the manufacturer
- Performed by
- Dr Nina Bal & the Facial Sculpting team
- Price
- From £1,400 per course — confirmed at consultation
The treatment
What is JULÄINE™ Bio-Stimulator Treatment?
JULÄINE™ is a PLLA (poly-L-lactic acid) bio-stimulator — a biocompatible, biodegradable material that has been used safely in medical devices for years. Rather than filling lines or adding volume directly, it acts as a stimulus: once injected, it encourages your own fibroblasts (the cells that produce collagen and elastin) to gradually rebuild the skin’s supportive framework. The aim is to restore the skin’s natural firmness, smoothness and radiance from within.
Because it works with your body’s own regenerative processes, JULÄINE™ is delivered as a course — typically two to three sessions about a month apart — and the result develops gradually over the following weeks rather than appearing immediately. Many patients value this for its natural progression: there is no sudden change, just skin that looks progressively fresher and firmer. According to the manufacturer, results can last 12–24 months, with maintenance over time.
JULÄINE™ sits among our collagen-stimulating and bio-remodelling injectables alongside Profhilo® and polynucleotides. It can be combined thoughtfully with other treatments as part of a wider plan — and the honest limitations below explain where another route may suit you better.
Concerns it can help
What does JULÄINE™ Bio-Stimulator Treatment address?
JULÄINE™ is designed to stimulate your own collagen for gradual firmness — not to fill lines or add instant volume.
Honest suitability
Is JULÄINE™ Bio-Stimulator Treatment right for you?
JULÄINE™ is not for everyone — and we will tell you if it is not the best option for you. Final suitability is always confirmed at consultation.
Often well suited
- Loss of firmness and elasticity you would like to improve
- Tired or lacklustre skin that needs renewal
- Wanting gradual, natural-looking collagen stimulation
- Preferring a result that builds over time, not instantly
- Happy to follow a planned course of 2–3 sessions
- Realistic expectations of a subtle, progressive change
May not be suitable
- Wanting an instant result or immediate volume (a filler may suit better)
- Known allergy to PLLA or the product’s constituents
- Pregnancy or breastfeeding (subject to clinic policy)
- Active infection, inflammation or skin condition in the area
- Certain medical or autoimmune conditions identified at consultation
- A history of keloid or hypertrophic scarring (assessed individually)
The process
How JULÄINE™ Bio-Stimulator Treatment works, step by step
- Consultation & assessmentDr Nina or the team assess your skin, medical history and goals, and confirm whether JULÄINE™ is suitable or whether another collagen-stimulating or bio-remodelling option fits better.
- PreparationThe treatment area is cleansed and mapped; a numbing cream may be applied for your comfort.
- Bio-stimulator injectionsThe PLLA-based product is injected with care into the planned areas, where it begins to stimulate your own collagen-building cells.
- Your courseJULÄINE™ is delivered as a course — usually two to three sessions about a month apart — so collagen can build gradually over time.
- Aftercare & reviewYou receive tailored aftercare advice, your progress can be reviewed as results develop, and a long-term maintenance plan is discussed where appropriate.
“A less-is-more philosophy: collagen stimulation only when it’s genuinely right for you — for firmer skin that builds naturally and still looks like you.”
The Facial Sculpting approach · Dr Nina BalBefore treatment
What happens at your consultation
A consultation is recommended before JULÄINE™. During your initial consultation with Dr Nina and her team you will have a clinical skin assessment and your suitability reviewed. You will be talked through the procedure in detail — what to expect during and after — and given the opportunity to ask questions.
The consultation covers your medical history, a skin assessment, your suitability and any contraindications, realistic expected outcomes, alternatives if JULÄINE™ is not ideal, aftercare, and confirmation of your individual plan and price.
Results & recovery
What to expect afterwards
JULÄINE™ involves minimal downtime and most people return to normal activities quickly. Temporary redness, mild swelling, tenderness or small bruises may occur at the injection points and usually settle within a few days. Your team may advise gentle massage of the area as part of aftercare, and you receive guidance tailored to your treatment.
Results & longevity: JULÄINE™ works gradually — collagen builds over the weeks following each session, so the improvement is progressive rather than immediate. According to the manufacturer, results can last 12–24 months, with annual or bi-annual maintenance to preserve them. Outcomes vary with skin quality, age and lifestyle.
Typical results timeline
First days
Any redness, swelling or small bruises at the injection points settle.
Over the course
Collagen stimulation builds session by session across your planned sessions.
Following weeks & months
Firmness, smoothness and radiance develop gradually as new collagen forms.
12–24 months
Results can be maintained over this period (per the manufacturer), with maintenance advised.
Safety
Possible risks & side effects
As with any injectable treatment, JULÄINE™ carries some risks. Possible side effects may include temporary redness, swelling, tenderness, small bruises or, less commonly, small lumps or nodules at the treated area, which are discussed in full at consultation. Following aftercare advice, including any recommended massage, helps support an even result.
Careful patient selection, an accurate plan and an experienced practitioner are important for a safe, natural result with a bio-stimulator. If anything is unexpected after treatment, you can contact the clinic for advice.
Honest limitations
What JULÄINE™ Bio-Stimulator Treatment cannot do
- It is not a filler — it does not add instant volume or fill lines directly.
- It cannot correct significant sagging or replace surgery.
- It does not deliver an immediate result — collagen builds gradually.
- It is not a substitute for sun protection and good skincare.
Compare your options
JULÄINE™ Bio-Stimulator Treatment vs other approaches
A simple, honest comparison of the collagen-stimulating and bio-remodelling injectables to help you and Dr Nina choose.
| Approach | Best for | Invasiveness | Downtime |
|---|---|---|---|
| JULÄINE™ Bio-Stimulator | Gradual collagen stimulation over a course | Minimally invasive injectable | Minimal |
| Profhilo® | Hydration & overall skin quality | Minimally invasive injectable | Minimal |
| Profhilo® Structura | Firmness & structural support | Minimally invasive injectable | Minimal |
| Polynucleotides | Regeneration, skin quality & under-eyes | Minimally invasive injectable | Minimal |
| Endolift® | Early–moderate laxity, deeper tightening | Minimally invasive laser | Minimal (~1 day) |
JULÄINE™ is often considered alongside Profhilo® and polynucleotides for skin quality, or with Endolift® for deeper laxity — the right plan is discussed honestly at consultation.
Transparent pricing
How much does JULÄINE™ Bio-Stimulator Treatment cost?
Prices start from £1,400 per course — your exact plan is confirmed after consultation.
JULÄINE™ Bio-Stimulator (Per Course)
From£1,400
A collagen-stimulating course of treatment; the recommended protocol is usually 2–3 sessions about a month apart, with the full plan confirmed at consultation.
Book this planThe exact price depends on your individual plan, which is confirmed after your consultation. View the full price list.
Why Facial Sculpting
JULÄINE™ Bio-Stimulator Treatment at the Facial Sculpting Clinic
Doctor-led & honest
Assessment first. If JULÄINE™ isn’t right for you, we’ll say so and recommend a safer or better option.
Tailored to you
A bespoke course for your skin, your concern and your goals — never one-size-fits-all.
Gradual & natural
A minimally invasive bio-stimulator that works with your own collagen, building results over time.
Dr Nina Bal
Cosmetic Doctor & Founder · South Kensington, London
Patients choose Facial Sculpting for JULÄINE™ because the focus is on careful assessment, natural-looking, gradual results and honest advice — not over-treating. Dr Nina and her clinical team plan the course around your goals and combine it thoughtfully with treatments such as Profhilo®, polynucleotides or Endolift® where appropriate.
GDC registeredBCAM memberSave Face PlatinumJCCP
GHP Best Facial Transformation Clinic London 2025Endolift UK Achievement Award 2025Safety in Beauty Best Aesthetic DoctorSafety in Beauty Best Non-Surgical TransformationGHP Best Non-Surgical Aesthetics Studio 2024Aesthetics Awards Finalist 2024Save Face Platinum
Accreditations & recognition
Save Face Platinum accredited
Registered with the General Dental Council
British College of Aesthetic Medicine member
Save Face COVID-19 Operational Protocol Certified
ICO — Information Commissioner's Office
JCCP — Joint Council for Cosmetic Practitioners
Featured in the Tatler Address Book
Hello! Aesthetics Guide
Safety in Beauty memberTrusted by patients
What our patients say about Facial Sculpting Clinic
Real reviews from patients who chose Dr Nina Bal and the Facial Sculpting team.
5.0
★★★★★
Rated 5.0 by patients on Google
via Google
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Jessica B.Patient review
★★★★★
Dr Nina is trustworthy, gentle, professional, friendly and glamorous! I recommend her to people all the time.
Verified patient
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Nez H.Patient review
★★★★★
I had EndoLift with Dr Nina at her clinic. I just wanted to share my experience With anyone who is looking to get endo lift or any other procedure done with Dr Nina. She is absolutely amazing so gentle and so kind she is so experienced in her field and knows whats best for you without trying to oversell you rather only whats needed. I was looking for this treatment for my double chin and picked the best place for it! it was a very comfortable treatment took about 30 mins. It permanently dissolves the fat there and tightens the area. She always checked on me to make sure im feeling ok. Its a week now and i can slowly see a difference im a little swollen and sore but the swelling is not noticeable to anyone. Cant wait for full results. Thank you Dr Nina.
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Catherine L.Patient review
★★★★★
Dr Nina’s recommendations for prescription skincare were truly first rate. Despite a spell of travel, planes and air conditioning, my skin has never looked better. She took time to answer my questions in full and I always felt in very safe hands. Thank you!
Verified patient
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Hilary V.Patient review
★★★★★
It is always such a joy to see Nina - not only because of the consistently amazing results of her professional skills but because she is a kind and warm individual who really listens to her clients. Her knowledge and treatments are constantly evolving and whilst she will always give her own recommendations I have never felt unable to make my own choices which is so valuable as a client. Her clinic is a very welcoming environment and I am very grateful to Nina for all of her expert advice, skill and support throughout the years and I look all the better for it! As an added bonus it’s like catching up with an old friend at every visit. She is truly one in a million!
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Freya K.Patient review
★★★★★
I recently visited Dr Nina at her Belgravia clinic and had the most wonderful experience, she is so skilled at what she does, super professional and not mention just lovely! She made me feel completely at ease and comfortable whilst talking through the procedures with great knowledge. I had Botox and profhilo with Dr Nina and it’s been a little over a week since the treatments and I am completely over the moon with my results, my skin has never been so glowy and radiant. I can’t wait for my next session in a few weeks.
Verified patient
Your questions
JULÄINE™ Bio-Stimulator Treatment FAQs
What is JULÄINE™ Bio-Stimulator Treatment?
JULÄINE™ is a PLLA (poly-L-lactic acid) bio-stimulator delivered by injection. Rather than filling lines or adding volume directly, it encourages your own fibroblasts to gradually produce fresh collagen and elastin, helping to restore firmness, smoothness and radiance from within over a planned course.
What is PLLA?
PLLA (poly-L-lactic acid) is a biocompatible, biodegradable material that has been used safely in medical devices for many years. In JULÄINE™ it acts as a bio-stimulator, prompting your skin to produce its own new collagen rather than relying on added filler.
How is JULÄINE™ different from dermal fillers?
Fillers add immediate volume by placing a gel beneath the skin. JULÄINE™ instead stimulates your own collagen production, so the result develops gradually and looks natural. If your goal is instant volume or contouring, a filler may suit you better; if you want progressive collagen stimulation, JULÄINE™ may be more appropriate. Dr Nina will advise.
What does JULÄINE™ achieve?
By supporting your own collagen and elastin, JULÄINE™ aims to smooth fine lines, improve elasticity, enhance overall skin quality and restore natural firmness for a refreshed appearance. Results develop over the weeks following each session and continue to build during the course. Individual results vary.
How many JULÄINE™ sessions will I need?
The recommended protocol is usually a course of two to three sessions spaced about a month apart, with maintenance over time. The exact number depends on your skin and goals and is confirmed at consultation.
When will I see results?
JULÄINE™ works gradually, so you will not see an instant change. Collagen builds over the weeks following each session, with the improvement developing progressively across and after the course. Many patients value this for its natural progression.
How long do JULÄINE™ results last?
According to the manufacturer, results from JULÄINE™ can last 12–24 months — longer than many treatments — because the improvement comes from your own newly stimulated collagen. Annual or bi-annual maintenance is usually advised to preserve the effect. Longevity varies between individuals.
How much does a full JULÄINE™ course cost?
JULÄINE™ at Facial Sculpting starts from £1,400 per course. Because the recommended protocol is a course of 2–3 sessions, the source page notes a typical total investment for a full course in the region of £2,800–£4,200, depending on how many sessions you need. Your exact plan and price are confirmed at consultation.
Is there any downtime?
Downtime is minimal and most people return to normal activities quickly. Temporary redness, mild swelling, tenderness or small bruises may occur at the injection points and usually settle within a few days. Your team may recommend gentle massage of the area as part of aftercare.
Is JULÄINE™ painful?
The injections are generally well tolerated, and a numbing cream may be applied for your comfort. Any tenderness afterwards is usually mild and short-lived. Your practitioner will explain exactly what to expect during and after treatment.
Is JULÄINE™ safe?
PLLA bio-stimulators have a long history of safe use in medicine, and JULÄINE™ is administered by a trained practitioner after proper assessment. As with any injectable, possible side effects (such as redness, swelling, bruising or, less commonly, small lumps) are discussed in full at consultation, and Dr Nina will only proceed where she believes it is appropriate for you.
Who is not suitable for JULÄINE™?
It may not be appropriate during pregnancy or breastfeeding, with a known allergy to PLLA, active infection or skin conditions in the area, certain medical or autoimmune conditions, or a history of keloid scarring. It is also not the right choice if you want an instant result. Suitability is always confirmed at consultation.
Can JULÄINE™ be combined with other treatments?
Yes. JULÄINE™ is often planned alongside treatments such as Profhilo®, polynucleotides or energy-based options like Endolift® as part of a wider plan. Dr Nina will advise on what is appropriate to combine and in what order, and the right timing around your course.
Can JULÄINE™ replace a facelift?
No. JULÄINE™ stimulates collagen to improve firmness and skin quality, but it cannot correct significant sagging or remove excess skin. Where laxity is more advanced, a different treatment or a surgical opinion may be more appropriate. Dr Nina will tell you honestly what it can and cannot achieve for your concern.
Is a consultation required before JULÄINE™?
A consultation is recommended to assess your skin, medical history and goals, confirm whether JULÄINE™ is suitable (or whether another treatment is better), and agree your individual course and price.
Take the next step
Book your JULÄINE™ Bio-Stimulator Treatment consultation
If you are considering JULÄINE™ Bio-Stimulator Treatment, a consultation is the safest way to confirm whether it is right for your skin, anatomy and goals — and to receive an honest recommendation and exact pricing.
Medical disclaimer: This page is for general information about a non-surgical aesthetic treatment and is not medical advice. Suitability, benefits, risks and results vary from patient to patient. Dr Nina Bal and her team will assess whether JULÄINE™ Bio-Stimulator Treatment is appropriate for you during a consultation. Before-and-after photographs are of individual patients for illustration only and are not a guarantee of any specific outcome.
